TABLE 2.
Sequence homologies of representative glucan binding domains in S. downei, S. sobrinus, and S. mutans GTFs, S. mutans GBP-A, and the synthetic peptides GLU and DREP
| Source (reference) | Amino acid position | Representative sequence | % Homology with GLU peptide | Amino acid position | Representative sequence | % Homology with DREP peptide |
|---|---|---|---|---|---|---|
| S. downei GTF-I (9) | 1303 | TGAQTIKGQKLYFRANGQQVKG | 100 | 1400 | VTGNDGKLRYYDANSGDQAFN | 57 |
| S. sobrinus GTF-I (1) | 1298 | TGAQTIRGQKLYFKANGQQYEG | 86 | 1436 | VTGTDGKVRYYDANSGDGAFN | 48 |
| S. sobrinus GTF-S (3) | 1234 | TGEQTIDGQKVFFQDNGVQVKG | 82 | 1117 | VWYDGKKAYYYDDNGRTWTNK | 29 |
| S. mutans GTF-I (12) | 1289 | TGARTINGQLLYFRANGVQVKG | 77 | 1324 | VTDRYGRISYYDGNSGDQIRN | 100 |
| S. mutans GTF-SI (12) | 1264 | TGTVTFNGQRLYFKPNGVQAKG | 73 | 1287 | IRDANGYLRYYDPNSGNEVRN | 48 |
| S. mutans GTF-S (4) | 1267 | VGVQTINGKTYYFGQDGKQIKG | 50 | 1314 | ATTDSQNNQYYFGSDGVAVTG | 24 |
| S. mutans GBP-A (2) | 274 | IGWRTIGLL.YYFDTNGVQVEG | 50 | 388 | DIAERDGKVYYLDEDSGQVVK | 19 |
| Synthetic peptides | ||||||
| GLU | TGAQTIKGQKLYFKANGQQVKG | |||||
| DREP | VTDRYGRISYYDGNSGDQIRN |