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| Compound | A375 IC50 (μM) | HSF IC50 (μM) | Selectivity index (SI) |
|---|---|---|---|
| 4f | 1.114 ± 0.02 | 4.18 ± 0.25 | 3.6 |
| 4i | 1.28 ± 0.021 | 3.26 ± 0.29 | 2.5 |
| 4j | 0.96 ± 0.03 | 9.58 ± 0.73 | 9.9 |
| 5f | 1.09 ± 0.09 | 3.59 ± 0.32 | 3.3 |
| 5i | 1.02 ± 0.07 | 3.63 ± 0.76 | 3.5 |
