Table 3. In vitro BRAFV600E and VEGFR-2 inhibitory activities.
| Compound | BRAFV600E (IC50, μM) | VEGFR-2 (IC50, μM) |
|---|---|---|
| 4j | 1.03 ± 0.71 | 0.64 ± 0.08 |
| Sorafenib | 2.86 ± 0.45 | 1.94 ± 0.05 |
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