Figure 1.

Variant processing pipeline schematic

We compared the probability that eQTLs and GWAS hits affect gene expression (eQTLs) or phenotype (GWAS hits) for variants in eCLIP peaks, RBP motifs, and various 3′ UTR annotation categories. We compared the likelihood of overlapping an RBP motif for variants with and without allele-specific eCLIP binding. SNV, single nucletoide variant; eCLIP, enhanced crosslinking and immunoprecipitation; RBNS, RNA Bind-n-Seq; PIP, posterior inclusion probability; RBP, RNA binding protein.