Figure 2.

Bubble plots showing the likelihood of individual genes within a pathway as driver across different tumor sites

(A) RTK-RAS pathway.

(B) PI3K pathway.

(C) Wnt pathway. TCGA disease codes and abbreviations: BRCA, breast cancer; LGG, lower-grade glioma; UCEC, uterine corpus endometrial carcinoma; LUAD, lung adenocarcinoma; HNSC, head and neck squamous cell carcinoma; THCA, papillary thyroid carcinoma; PRAD, prostate adenocarcinoma; LUSC, lung squamous cell carcinoma; BLCA, urothelial bladder cancer; SKCM, cutaneous melanoma; KIRC, clear cell kidney carcinoma.