Table 1.

Single-SNP 95% credible sets of prostate cancer

Fine-mapping regiona	Variantb	rsIDc	AAFd	p valuee	CLf	Putative target gene(s)g	Association type(s)h
chr2:62,482,371–64,700,760	2_63301164_G_A	rs6545977	0.50	7.35 × 10−46	1	–	–
chr2:241,912,029–243,041,411	2_242135265_G_A	rs77559646	0.02	9.93 × 10−21	1	ANO7	NSMi, INTj
chr3:169,194,244–170,170,389	3_170083629_C_G	rs61436251	0.21	1.76 × 10−63	1	SKIL	INT
chr5:1,279,701–1,551,138	5_1288547_T_C	rs2853676	0.73	8.86 × 10−12	0.99	TERT	INT
chr5:1,551,930–2,131,681	5_1895829_C_T	rs12653946	0.42	9.58 × 10−22	0.99	IRX4	cis eQTL (GTEx)
chr6:159,951,830–161,847,113	6_160581374_A_G	rs651164	0.69	2.15 × 10−36	1	SOD2, ACAT2, TCP1, MRPL18	Enhancer (H3K27ac, HiChIP, LNCaP)
chr6:159,951,830–161,847,113	6_160581502_T_C	rs4646283	0.14	1.31 × 10−5	0.99	SOD2, ACAT2, TCP1, MRPL18	Enhancer (H3K27ac, HiChIP, LNCaP)
chr8:127,708,268–128,658,961	8_128108726_G_A	rs35365584	0.33	3.60 × 10−67	1	MYC	Enhancer (H3K27ac, HiChIP, LNCaP)
chr8:127,708,268–128,658,961	8_128540776_C_G	rs12549761	0.12	5.20 × 10−77	1	–	–
chr8:128,659,713–129,297,518	8_128665480_C_T	rs4385433	0.37	6.91 × 10−8	0.96	–	–
chr10:50,839,567–53,146,331	10_51549496_T_C	rs10993994	0.62	2.29 × 10−147	1	TIMM23B, MSMB, NCOA4	INT, R5k, cis eQTL (GTEx)
chr11:124,697,216–125,111,546	11_125054793_C_T	rs138466039	0.01	2.01 × 10−11	1	PKNOX2	INT, cis eQTL (GTEx)
chr12:12,101,106–12,922,339	12_12871099_T_G	rs2066827	0.24	2.31 × 10−9	1	CDKN1B	NSM,R3l
chr13:73,847,474–74,347,673	13_74084684_G_A	rs61957204	0.07	3.29 × 10−11	1	–	–
chr14:23,251,130–23,598,976	14_23305649_T_C	rs1004030	0.42	1.55 × 10−8	0.98	MMP14	R5
chr17:7,251,713–8,007,416	17_7571752_T_G	rs78378222	0.01	1.73 × 10−9	1	TP53	U3m
chr19:51,254,187–51,450,534	19_51361382_G_A	rs61752561	0.04	2.33 × 10−8	1	KLK3	NSM, INT
chr22:42,872,086–43,649,657	22_43500212_G_T	rs5759167	0.50	5.55 × 10−71	1	–	–

^aChromosome (chr) number and boundary of fine-mapping region (GRCh37/hg19).

^bVariant ID in the format {chr}_{pos}_{ref_seq}_{alt_seq}.

^cdbSNP (build 151, GRCh37/hg19) rsID.

^dAlternative allele frequency of controls in meta-analysis.

^eMeta-analysis p value.

^fh2-D2 credible level.

^gPutative target gene(s) of the variant.

^hAssociation type(s) between the variant and its putative target gene(s).

ⁱNon-synonymous missense.

^jIn, intron.

^kIn 5′ gene region.

^lIn 3′ gene region.

^mIn 3′ UTR.