Table 3.
trichoscopy and histopathology features of normal appearing scalp in SLE patients with and without hair loss who had scalp biopsy
Variable | Normal appearing scalp in SLE hair loss group n=12 (%) | No hair loss group n=11 (%) | p |
---|---|---|---|
Trichoscopy findings | |||
Hair shaft changes | |||
Short regrowing hair, n (%) | 3 (25.0) | 0 (0.0) | 0.217* |
Hair shaft hypopigmentation, n (%) | 9 (75.0) | 1 (9.1) | 0.003* |
Follicular opening/dots | |||
White dots, n (%) | 2 (16.7) | 11 (100.0) | <0.001 |
Brown scattered pigmentation, n (%) | 1 (8.3) | 0 (0.0) | 1.000* |
Arborizing/ interconnecting vessels, n (%) | 1 (8.3) | 0 (0.0) | 1.000* |
Histology | |||
Epidermal atrophy, n (%) | 6 (50.0) | 2 (18.2) | 0.193* |
Interface change | |||
Along dermoepidermal junction, n (%) | 1 (8.3) | 0 (0.0) | 1.000* |
Along follicular epithelium, n (%) | 1 (8.3) | 0 (0.0) | 1.000* |
Infiltrates | |||
Lymphocytic infiltrates, n (%) | 4 (33.3) | 0 (0.0) | 1.000* |
Superficial perivascular, n (%) | 3 (25.0) | 0 (0.0) | 1.000* |
Perifollicular, n (%) | 1 (8.3) | 1 (9.1) | 0.317* |
Presence of plasma cells, n (%) | 1 (8.3) | 1 (9.1) | 0.590* |
Sebaceous glands | |||
Reduction in size/ number of sebaceous gland | 7 (58.3) | 1 (9.1) | 0.027* |
Mucin deposition | |||
Mild | 5 (41.7) | 4 (36.4) | |
Moderate | 5 (41.7) | 5 (45.5) | 0.967 |
Severe | 2 (16.7) | 2 (18.2) | |
Follicular characteristics | |||
Telogen counts, median (range) | 2.5 (0 - 9) | 2 (0 - 6) | 0.478 |
Number of hairs, median (range) | 18 (7 - 35) | 25 (5 - 34) | 0.308 |
Follicular units, median (range) | 8.5 (5 - 13) | 10 (2 - 12) | 0.596 |
Anagen follicle, median (range) | 14 (3 - 30) | 21 (2 - 30) | 0.423 |
Telogen percentage, median (range) | 17 (0 - 62) | 8 (0 - 26) | 0.085 |
Terminal: Vellus ratio, median (range) | 7 (4 - 17) | 7 (4 - 20) | 0.803 |
: Fischer’s exact p-value