Table 4.
comparison of features between the different types of non-scarring hair loss
| Variable | Patchy (n-16) | Mild diffuse (n = 9) | Severe diffuse (n = 11) | p |
|---|---|---|---|---|
| Sociodemographic | ||||
| Age (years) mean (sd) | 34.4 (12,2) | 34.4 (15.8) | 41.4 (15.9) | 0.409 |
| Duration of SLE, years, median (range) | 3 (0.3, 8) | 5 (1.0, 16) | 0.7 (0.3-8.0) | 0.025 |
| Duration of hair loss years, median (range) | 1 (0.3, | 2 (0.5 - 17) | 0.7 (0.1-5.0) | 0.418 |
| Duration of SLE treatment, median (range) | 2.5 (0.1, 8) | 3.5 (0.5 -15) | 3.5 (0.3-12) | 0.043 |
| Trichoscopic findings | ||||
| Hair shaft changes | ||||
| Short re-growing hair, n (%) | 2 (12.5) | (44.4) | 5 (45.4) | 0.108 |
| Hair shaft thining, n (%) | 0 (0.0) | 2 (22.2) | 3 (27.3) | 0.310 |
| Hair shaft hypopigmentation, n (%) | 1 (6.3) | 2 (22.2) | 2 (18.2) | 0.479 |
| Follicular opening/dots | ||||
| Black dots, n (%) | 3 (18.8) | 1 (11.1) | 2 (18.2) | 0.874 |
| White dots, n (%) | 16 (100.0) | 9 (100.0) | 10 (90.9) | Invalid |
| Follicular red dots, n (%) | 4 (25.0) | 3 (33.3) | 3 (27.3) | 0.904 |
| Blue grey pigmentation, n (%) | 1 (6.3) | 0 (0.0) | 3 (27.3) | 0.110 |
| Brown scattered pigmentation, n (%) | 3 (18.8) | 4 (44.4) | 9 (81.8) | 0.005 |
| Arborizing/ interconnecting vessels, n (%) | 2 (12.5) | 3 (33.3) | 5 (45.4) | 0.156 |
| Thick vessels, n (%) | 2 (12.5) | 0 (0.0) | 2 (18.2) | 0.881 |
| Histology | ||||
| Epidermal atrophy, n (%) | 1 (33.3) | 2 (66.7) | 3 (50.0) | 0.717 |
| Interface change, n (%) | 0 (0.0) | 0 (0.0) | 2 (33.3) | 0.301 |
| Along dermoepidermal junction, n (%) | 0 (0.0) | 0 (0.0) | 1 (16.7) | 0.580 |
| Along follicular epithelium, n | 0 (0.0) | 0 (0.0) | 1 (16.7) | 0.580 |
| Lymphocytic infiltration, n (%) | 0 (0.0) | 1 (33.3) | 3 (50.0) | 0.325 |
| Superficial perivascuylar, n (%) | 0 (0.0) | 1 (33.3) | 2 (33.3) | 0.513 |
| Perifollicular,n (%) | 0 (0.0) | 0 (0.0) | 1 (16.7) | 0.580 |
| Presence of plasma cells, n (%) | 1 (33.3) | 0 (0.0) | 0 (0.0) | 0.195 |
| Reduction in size/ number of sebaceous gland | 1 (33.3) | 3 (100.0) | 3 (50.0) | 0.214 |
| Mucin deposition | ||||
| Mild | 0 (0.0) | 0 (0.0) | 2 (33.3) | |
| Moderate | 0 (0.0) | 2 (66.7) | 2 (33.3) | 0.134 |
| Severe | 3 (100.0) | 1 (33.3) | 2 (33.3) | |
| Follicular features | ||||
| Telogen count | 5 (1 - 6) | 1 (1- 3) | 5 (1 - 5) | 0.309 |
| Number of hairs, median (range) | 14 (11 - 24) | 10 (4 - 13) | 22 (16 - 30) | 0.047 |
| Follicular units, median (range) | 7 (5 - 11) | 4 (3 - 8) | 10 (7 - 13) | 0.150 |
| Anagen follicle, median (range) | 10 (6 - 19) | 9 (3 - 10) | 21.5 (18 - 25) | 0.050 |
| Telogen percentage, median (range) | 21 (9 - 57) | 18 (8 - 25) | 9 (4 - 16) | 0.201 |
| Terminal: Vellus ratio, median (range) | 4 (2 - 6) | 9 (4 - 13) | 10 (5 - 23) | 0.100 |