Extended Data Fig. 2. Histological evaluation of patient 7′s sequential tumors demonstrating distinct histological and immunohistochemical features.

(Patient example Fig. 1a, patient 7 Fig. 1b, Extended Data Tables 3/4). a, Tumor 3: Gastric adenocarcinoma. b, Tumor 4: Colorectal adenocarcinoma. c, Tumor 5: Prostate adenocarcinoma. d, Tumor 6: Small bowel adenocarcinoma. The relevant stain, hematoxylin and eosin, was run on each chosen study tissue block once. All antibodies and staining protocols are validated and optimized to current standards.