Table 2.
Outcomes | ACE inhibitor | ARB | Calibrated HR [95% CI] |
ACE inhibitor | Thiazide | Calibrated HR [95% CI] |
||||
---|---|---|---|---|---|---|---|---|---|---|
N | IRa | N | IR§ | N | IR§ | N | IRa | |||
South Korea | ||||||||||
Total population | 21 410 | 0.44 | 577 637 | 0.22 | 1.47 [0.70–3.10] | 9 852 | 0.57 | 70 491 | 0.53 | 0.88 [0.22–3.46] |
≥45 years | 15 405 | 0.57 | 431 745 | 0.27 | 1.36 [0.64–2.88] | 7 639 | 0.66 | 55 106 | 0.57 | 1.98 [0.42–9.21] |
United States | ||||||||||
Total population | 2 130 393 | 0.43 | 2 151 531 | 0.37 | 1.14 [0.98–1.32] | 1 777 108 | 0.54 | 1 864 047 | 0.65 | 0.91 [0.78–1.07] |
≥45 years | 1 792 503 | 0.41 | 1 813 979 | 0.35 | 1.22 [1.04–1.43]b | 1 316 424 | 0.47 | 1 359 260 | 0.54 | 0.89 [0.74–1.07] |
aIncidence rates were calculated as case per 1 000 person-years; bstatistically significant
ACE, Angiotensin Converting Enzyme; ARB, Angiotensin II Receptor Blockers, IR: Incidence rates; HR: hazard ratio; CI: 95% confidence interval