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. 2024 Feb 16;24:128. doi: 10.1186/s12888-024-05578-6

Table 2.

Risk of outcome events between the ACE inhibitor versus the ARB groups or between the ACE inhibitor versus Thiazide groups

Outcomes ACE inhibitor ARB Calibrated HR
[95% CI]
ACE inhibitor Thiazide Calibrated HR
[95% CI]
N IRa N IR§ N IR§ N IRa
South Korea
 Total population 21 410 0.44 577 637 0.22 1.47 [0.70–3.10] 9 852 0.57 70 491 0.53 0.88 [0.22–3.46]
 ≥45 years 15 405 0.57 431 745 0.27 1.36 [0.64–2.88] 7 639 0.66 55 106 0.57 1.98 [0.42–9.21]
United States
 Total population 2 130 393 0.43 2 151 531 0.37 1.14 [0.98–1.32] 1 777 108 0.54 1 864 047 0.65 0.91 [0.78–1.07]
 ≥45 years 1 792 503 0.41 1 813 979 0.35 1.22 [1.04–1.43]b 1 316 424 0.47 1 359 260 0.54 0.89 [0.74–1.07]

aIncidence rates were calculated as case per 1 000 person-years; bstatistically significant

ACE, Angiotensin Converting Enzyme; ARB, Angiotensin II Receptor Blockers, IR: Incidence rates; HR: hazard ratio; CI: 95% confidence interval