Figure 37.
In vivo control of a mouse mediated by magnetism. Transgenic mice expressing a Myc-tagged mechanosensitive ion channel in the M2 of the premotor cortex were injected with an anti-Myc mAb conjugated to a magnetic nanoparticle called m-Torquer. Injection into the right-hemisphere only and placement of the mouse into a rotating magnetic field led to more active mice that traveled in a counterclockwise direction.239 CMA = circular magnet array.