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Tissuoselectivity gained by “piggy-backing” microbes. The pro-tumoral bacteria F. nucleatum was targeted by a selective azido-phage. Tumours thus displaying azides could be targeted with DBCO-labeled reagents (e.g., nanoparticles that release cytotoxic agent irinotecan).54 Abbreviations are as follows: IDNP = irinotecan-loaded dextran nanoparticle.
