Table 3.
Substitution analysis for the association of replacing macronutrients together on the odds of breast cancer calculated using logistic regression modelsa
| Substituting X instead of Y | per 50 Kcal | per 100 Kcal | ||
|---|---|---|---|---|
| OR differences (95% CI) | P-value | OR differences (95% CI) | P-value | |
| Protein instead of CHO | -0.10 (-0.31, 0.10) | 0.325 | -0.21 (-0.63, 0.21) | 0.325 |
| Protein instead of fat | -0.20 (-0.36, -0.03) | 0.016 | -0.40 (-0.73, -0.07) | 0.016 |
| Plant protein instead of animal protein | -0.14 ( -0.44. 0.15) | 0.351 | -0.28 (-0.88, 0.31) | 0.351 |
| Plant protein instead of refined CHO | -0.33 (-0.63, -0.03) | 0.028 | -0.66 (-1.26, -0.07) | 0.028 |
| Plant protein instead of animal fat | -0.20 (-0.46, 0.05) | 0.126 | -0.40 (-0.92, 1.11) | 0.126 |
CHO Carbohydrate
aAll analyses were adjusted for age, first pregnancy age, menopausal status, family history of cancer, anti-inflammatory drug use, vitamin D supplementation, physical activity, body mass index, socio-economic status, and energy intake