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A schematic depicting the role of viruses in the pathogenesis of glaucoma. Many oculotropic viruses (e.g., HSV, VZV, CMV, EBV, CHIKV, RUBV, EBOV, DENV, WNV, HBV, HCV, ZIKV, and SARS-CoV-2) cause immune cell-mediated ocular inflammation, called uveitis, that results into elevated IOP. This virus-induced IOP often leads to the development of glaucomatous pathology resulting in vision loss. Image created with BioRender.com.
