TABLE 1.
Clinical characteristics of patients with high-altitude NAION
| Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Summary (n = 5) | |
|---|---|---|---|---|---|---|
| Sex | M | F | M | M | M | M:F = 4:1 |
| Age (yrs) | 49 | 74 | 48 | 55 | 56 | 56 |
| Risk factors | None | multiple | Hyperlipidemia | None | Prior sildenafil use | None |
| Altitude exposure before onset (feet) | 8,000 | 7,000 | 8,000 | 5,000–9,000 | 9,000 | 8,000 |
| Sleep apnea | Mild | Moderate | Moderate | Deferred | Mild | Present |
| Subsequent CPAP treatment | Yes | Yes | Yes | NA | No | |
| AHI | 5.4 | 18.2 | 22.2 | NA | 8.7 | 5.4–22.2 |
| Nadir O2 saturation | 90% | 87% | 87% | NA | 97% | 87%–97% |
| ODI | 4.8 | 3.6 | NA | NA | NA | 3.6–4.8 |
| RDI | - | NA | NA | NA | NA |
AHI, apnea–hypopnea index; CPAP, continuous positive airway pressure; NA, not available.