Table 7.

Model at 32 Weeks Postmenstrual Age, Including Survivors to 32 Weeks Postmenstrual Age (Limited to Importance 0.0005 or More)

Variable (Selected by LASSO)	AUC C-Statistic	Importance of Variable	OR (95% CI)	P Value
Clinical variables alone model	0.871
SGA		0.0142	6.76 (2.92–15.64)	0.00001
IMV		0.0136	6.86 (3.43–13.71)	0.00000
Gestational age		0.0105	0.56 (0.43–0.72)	0.00001
Positive pressure		0.0079	2.51 (1.57–4.01)	0.0001
FiO2*		0.0050	2.17 (1.36–3.46)	0.001
Apgar 1-min score		0.0034	0.77 (0.62–0.95)	0.015
Diuretic		0.0033	2.96 (1.42–6.15)	0.004
Supplemental oxygen >12 h/24 h		0.0022	2.09 (1.27–3.44)	0.004
Black race		0.0011	0.66 (0.41–1.08)	0.098
Physiologic variables alone model	0.845
IH90 dpe		0.0146	2.57 (1.74–3.81)	<0.00001
PB count		0.0084	0.53 (0.33–0.87)	0.012
IH90 count		0.0067	1.54 (1.23–1.93)	0.0002
Apnea dpe		0.0028	0.80 (0.62–1.02)	0.07
Combined model (physiologic model + clinical model)	0.879
SGA		0.0101	5.33 (2.13–13.32)	0.0003
Gestational age		0.0052	0.58 (0.43–0.79)	0.0005
PB count		0.0037	0.63 (0.39–1.01)	0.054
Positive pressure		0.0025	1.94 (1.12–3.33)	0.017
IH90 count		0.0020	1.33 (1.03–1.70)	0.027
IMV		0.0018	2.63 (0.99–6.99)	0.053
Diuretic		0.0018	2.75 (1.24–6.08)	0.013
IH90 dpe		0.0016	1.62 (1.14–2.29)	0.007
Apgar 1-min score		0.0014	0.81 (0.64–1.03)	0.080
FiO2 >0.3*		0.0014	2.32 (1.25–4.31)	0.008
Apnea dpe		0.0012	0.82 (0.63–1.07)	0.144
Black race		0.0011	0.65 (0.41–1.05)	0.075

Definition of abbreviations: AUC = area under the curve; CI = confidence interval; dpe = duration per event; IH90 = intermittent hypoxemia events with oxygen saturation as measured by pulse oximetry <90%; IMV = invasive mechanical ventilation; LASSO = least absolute shrinkage and selection operator; OR = odds ratio; PB = periodic breathing; SGA = small for gestational age.

^*When Fi_O2 is listed as a variable, it is the continuous variable of Fi_O2 value closest to noon. If Fi_O2 >0.3 is listed, it is the binary variable Fi_O2 >0.3.