Table 1.

Description of the 18 Cases with Mutation

Case Number	Age at Surgery (d)	Mutation in Malformed Tissue	Allelic Ratio (%)	Mutation in Surrounding Healthy Tissue	Allelic Ratio (%)	Prenatal Imaging	Birth Weight (kg)	Neonatal Respiratory Distress*	Largest Cyst Diameter on Postnatal CT (mm)	Mucinous Component
1	641	KRAS p.Gly12Asp c.35G>A	13.2	KRAS p.Gly12Asp c.35G>A	15	Hyperechoic	2.8	No	9	No
2	1	KRAS p.Gly12Asp c.35G>A	13	KRAS p.Gly12Asp c.35G>A	4	Cystic	3.3	Yes	41	No
3	0	KRAS p.Gly12Asp c.35G>A	23	NA		Cystic	3.5	Yes	45	Yes
4	217	KRAS p.Gly12Asp c.35G>A	10	None	—	Cystic	3.7	No	12	Yes
5	320	KRAS p.Gly12Val c.35G>T	4	NA		Hyperechoic	3	Yes	7	No
6	192	KRAS p.Gly12Asp c.35G>A	11	NA		Cystic	3.5	No	33	No
7	211	KRAS p.Gly12Asp c.35G>A	20	NA		Cystic	3.2	No	34	Yes
8	410	KRAS p.Gly12Val c.35G>T	3	NA		Cystic	4.1	No	11	No
9	783	KRAS p.Gly12Asp c.35G>A	12	NA		Cystic	3.5	No	21	Yes
10	364	KRAS p.Gly12Val c.35G>T	20	NA		Cystic	3.4	Yes	40	No
11	118	KRAS p.Gly12Asp c.35G>A	19.4	None	—	Cystic	3.1	No	17	No
12	4	KRAS p.Gly12Asp c.35G>A	18.7	KRAS p.Gly12Asp c.35G>A	0.7	Cystic	2.6	Yes	20	Yes
13	13	KRAS p.Gly12Asp c.35G>A	33	KRAS p.Gly12Asp c.35G>A	9	Cystic	3.3	No	35	Yes
14	391	KRAS p.Gly12Asp c.35G>A	4.2	NA		Cystic	3	No	26	Yes
15	190	KRAS p.Gly12Asp c.35G>A	7.9	None	—	Cystic	3.8	No	33	No
16	234	KRAS p.Gly12Arg	27	NA		Cystic	3.6	No	24	No
17	2	KRAS p.Gly12Cys	17	NA		Cystic	2.9	Yes	53	Yes
18	0	FGFR2 p.Cys382Arg c.1144T>C	34	NA		Hyperechoic	3.2	Yes	NA	No

Definition of abbreviations: CT = computed tomography; NA = not applicable.

^*Neonatal respiratory distress was defined by having at least one of the following criteria: polypnea > 60/min or signs of retraction; need for oxygen therapy, noninvasive ventilatory support, or invasive ventilatory support; need for surgical congenital pulmonary malformation removal before the age of 7 days (3).