Safety measurement of MNPs-TRPV1. (A) H&E staining of the major organs (heart, liver, spleen, lung, and kidney) of mice treated as indicated revealed no obvious structural or cellular alterations. (B to G) The serum levels of alanine aminotransferase (ALT) (B), aspartate aminotransferase (AST) (C), albumin (ALB) (D), cholesterol (E), urea (F), and lactate dehydrogenase (LDH) (G) of mice treated with MNPs of MNPs-TRPV1 in the presence or absence of AMF stimulation. w/o, without; w/, with. Scale bars, 100 μm. One-way ANOVA with Tukey’s post hoc test. Data are shown as mean ± SD.