Table 2.
The mean values and the standard deviations of the pocket volume (Å3) and solvent accessible surface area (SASA) (Å2) of the active-site pocket.
| System | Volume (Å3) | SASA (Å2) |
|---|---|---|
|
| ||
| WT | 1071.81 ±157.54 | 154.99±2.51 |
| V211A | 1182.23±200.19 | 156.27±3.44 |
| V211G | 1181.68±187.35 | 154.82±2.49 |
| G214A | 1075.46±259.79 | 155.20±2.73 |
| G214R | 1115.24±241.80 | 156.65±2.84 |
| E219A | 1206.33±221.87 | 155.89±2.77 |
| E219G | 1211.74±250.02 | 155.99±3.22 |
| E219K | 1278.62±293.00 | 156.41 ±2.69 |
| Y221A | 1381.32±302.32 | 156.89±2.95 |
| Y221H | 1210.70±182.42 | 156.03±2.47 |