Table 2.
Results of meta-analysis comparison of LLR and RLR.
Outcomes of interest | Number of studies | Number of patients | I2 (%) | Model | Overall effect size | 95% CI of overall effect size | P |
---|---|---|---|---|---|---|---|
Primary outcomes | |||||||
Overall complications | 21 | 4908 | 41 | Fixed | OR=0.99 | [0.86, 1.14] | 0.91 |
Severe complications | 20 | 4880 | 0 | Fixed | OR=0.76 | [0.61, 0.95] | 0.02 |
R0 | 14 | 3399 | 0 | Fixed | OR=1.28 | [1.00, 1.63] | 0.05 |
Secondary outcomes | |||||||
Operating time (min) | 19 | 4502 | 68 | Random | SMD=0.07 | [−0.05, 0.18] | 0.25 |
Blood loss (ml) | 17 | 3912 | 84 | Random | SMD=−0.31 | [−0.48, −0.14] | 0.0005 |
Transfusion | 17 | 4350 | 29 | Fixed | OR=0.96 | [0.78, 1.19] | 0.72 |
Pringle applied | 16 | 4399 | 91 | Random | OR=0.73 | [0.44, 1.22] | 0.23 |
Pringle duration (min) | 13 | 2964 | 85 | Random | SMD=−0.01 | [−0.22, 0.19] | 0.89 |
Open conversion | 19 | 4894 | 45 | Fixed | OR=0.46 | [0.37, 0.58] | <0.0001 |
Hospital stay (day) | 18 | 4361 | 62 | Random | SMD=−0.02 | [−0.13, 0.08] | 0.66 |
Reoperation | 14 | 3914 | 0 | Fixed | OR=0.67 | [0.38, 1.18] | 0.20 |
30-day readmission | 14 | 3950 | 0 | Fixed | OR=1.12 | [0.83, 1.51] | 0.47 |
30-day mortality | 13 | 3769 | 0 | Fixed | OR=1.11 | [0.55, 2.24] | 0.77 |
90-day mortality | 15 | 4545 | 0 | Fixed | OR=0.79 | [0.47, 1.34] | 0.38 |
Statistically significant results are shown in bold.
LLR, laparoscopic liver resection; RLR, robotic liver resection; SMD/OR, standard mean difference/odds ratio.