Table 3b:
Bivariate and multivariable relationships between continuous baseline BMI and clinical outcomes
| Clinical Outcomes | Bivariate HR (95% CI) associated with 5 unit increase of BMI (kg/m2) | Multivariable HR (95% CI) associated with 5 unit increase of BMIa (kg/m2) |
|---|---|---|
| Death/MI | 1.09 (0.98,1.20) | 1.09 (0.97, 1.23) |
| All-cause death | 1.04 (0.92,1.16) | 1.06 (0.92, 1.21) |
| CV death | 1.02 (0.89,1.16) | 1.01 (0.87, 1.18) |
| MI | 1.22 (1.05,1.4) | 1.12 (0.93, 1.34) |
Multivariable model adjusted for baseline covariates: age, sex, hypertension, diabetes, current smoker, atrial fibrillation, prior MI or prior PCI or prior CABG, prior heart failure, ejection fraction, prior stroke, peripheral artery disease, baseline Seattle Angina Questionnaire Summary Score, Canadian Cardiovascular Society Angina (I/II/III), New York Heart Association I/II/III, baseline low density lipoprotein- and high-density lipoprotein-cholesterol, dialysis status at baseline;
BMI was modeled in its original form; Other continuous covariates are modeled as cubic splines
BMI, body mass index; CI, confidence interval; CV, Cardiovascular; HR, hazard ratio; MI, myocardial infarction.