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. 1998 Dec;66(12):5731–5742. doi: 10.1128/iai.66.12.5731-5742.1998

TABLE 2.

ORFs that may be potential virulence factors

ORF Location (bp) Homologous protein (target) % Homologya Accession no. Refer-ence(s)
ORF4 76298–76603 C-type natriuretic peptide from Squalus acanthias 43/30 P41319 83
ORF17 92476–92919 Delta insecticidal protein from Bacillus thuringiensis 40/18 P05628 35
ORF18 Complement, 92949–93512 RTXb toxin of Actinobacillus pleuropneumoniae 21/11 D16582 32, 65
ORF21 94015–94448 Laminin of Homo sapiens 23/5 Q16787 79, 95
Paramysin-related protein of Onchocerca gibsoni 21/18 U20609 25, 99
ORF72 23873–24244 Major myristoylated alanine-rich protein kinase C substrate 24/32 P29966 41
ORF74a 25221–25883 Bacteriophage lambda V protein 40/41 P03733 81
Citrobacter freundii intimin 30/10 Q07591 82
a

Percentage of identical amino acids compared with the percentage of the total target protein sequence. 

b

RTX represents repeats in the structural toxin.