Figure 3.

Nuclear proteins that colocalize in LNCs. Confocal images of untreated and ActD-treated cells showing: (A) Untreated: PSF nucleoplasmic staining and p80 coilin labeling of Cajal bodies. Treated: PSF and p80 coilin were found in two distinct nucleolar caps. (B) Untreated: fibrillarin was found mainly in nucleoli but also in Cajal bodies. Treated: partial overlap between p80 coilin caps and fibrillarin caps. (C) Fibrillarin and Nopp140 were found in the same nucleolar caps. (D) Fibrillarin and ALL-1 also colocalized in these caps. Bar, 10 μm.