Table 3.

Reasons for discontinuation by patient

	Weeks used before discontinuation by patient
	Total		1-2		3-6		7+
	%a	(SE)	%a	(SE)	%a	(SE)	%a	(SE)	χ2b	df
Lack of continued need
Felt better	46.6	(2.8)	51.4	(4.6)	32.8	(5.0)	50.0	(4.1)	7.6*	2
No longer neededc	1.8	(0.6)	0.0	(0.0)	2.0	(1.5)	2.7	(1.1)	0.0	1d
Total	48.4	(2.8)	51.4	(4.6)	34.9	(5.0)	52.7	(3.9)	7.3*	2
Treatment ineffectiveness
Medication not working	14.3	(1.2)	13.0	(2.1)	17.3	(3.1)	13.7	(1.8)	1.8	2
Side effects	5.1	(1.0)	2.1	(0.7)	6.5	(3.2)	6.1	(1.3)	7.2*	2
Total	18.5	(1.3)	14.3	(2.2)	21.0	(3.4)	19.8	(1.9)	5.2	2
Predisposing factorse
Fear of dependence	15.3	(1.5)	23.2	(3.7)	12.1	(3.7)	12.5	(1.6)	9.4*	2
Wanted to solve problem on own	7.1	(1.4)	6.8	(1.3)	8.8	(3.9)	6.5	(1.4)	0.6	2
Total	20.0	(2.0)	25.0	(3.5)	20.9	(4.9)	16.9	(2.3)	3.8	2
Enabling factors
Pressured to quitf	4.2	(0.8)	4.3	(0.5)	2.6	(1.6)	4.8	(1.6)	0.8	2
Couldn’t afford treatment	1.0	(0.4)	2.5	(1.3)	0.0	(0.0)	0.5	(0.0)	12.7*	1d
Total	5.0	(0.9)	6.2	(1.4)	2.6	(1.6)	5.4	(1.6)	1.7	2
Other reasons
Any other reason	14.2	(1.9)	8.9	(4.6)	26.4	(4.6)	11.9	(1.5)	12.6	2
(n)	(328)		(87)		(67)		(174)

^*Significant at the .05 level, two-sides design-based test.

^aEstimate treats row variable as numerator and column variable as denominator. For example, the % or "Felt Better" (46.6%) is the % of those that stopped medication because they felt better among the Total.

^bχ² tests evaluate the significance of differences in distributions across subgroups defined by the columns.

^cBelieved problem would get better without medication.

^d1 df test leaving out 0 cell.

^eWe also asked about embarrassment, but no patient reported this as a reason for discontinuation.

^fSomeone in personal life pressured the patient to quit.