Table 4.
Multivariable predictors of discontinuation by patient
| Total | Need | Ineffective | Predisposing | Enabling | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| RR | (95% CI) | RR | (95% CI) | RR | (95% CI) | RR | (95% CI) | RR | (95% CI) | |
| Person-weeks | ||||||||||
| 1-2 | 7.4* | (5.0-10.9) | 5.7* | (3.1-10.7) | 7.2* | (3.5-15.0) | 15.6* | (7.6-31.7) | 6.3* | (1.8-22.4) |
| 3-7 | 3.9* | (2.6-6.0) | 2.5* | (1.1-5.6) | 4.6* | (1.9-11.1) | 5.4* | (2.5-11.5) | 1.0 | (0.1-8.1) |
| 7-52 (REF) | ||||||||||
| χ22 | 116.1* | 31.2* | 33.0* | 58.9* | 8.4* | |||||
| County income level | ||||||||||
| LMIC 1-2 weeks | 4.0* | (2.2-7.5) | 7.2* | (3.1-16.8) | 0.7 | (0.1-4.0) | 0.4 | (0.1-2.1) | 8.5* | (1.8-40.3) |
| LMIC 3-6 weeks | 2.0 | (0.8-4.7) | 2.3 | (0.5-11.3) | 0.6 | (0.1-3.3) | 0.7 | (0.2-2.4) | 12.6* | (1.1-142.7) |
| LMIC 7-52 weeks | 0.9 | (0.4-1.7) | 0.9 | (0.4-2.3) | 0.3 | (0.0-1.8) | 0.5 | (0.1-2.2) | 1.0 | (0.1-8.1) |
| χ23 | 20.9* | 21.3* | 2.3 | 2.1 | 10.7* | |||||
| Socio-economic status | ||||||||||
| Employed | 1.4* | (1.0-1.9) | 2.0* | (1.2-3.3) | 0.7 | (0.1-1.4) | 1.0 | (0.6-1.9) | 1.6 | (0.5-4.8) |
| High/low-average educationa | 1.3 | (0.8-2.2) | 3.7* | (1.8-7.4) | 1.6 | (0.7-3.7) | 1.3 | (0.6-2.8) | 8.5* | (1.8-40.2) |
| High/high-average income | 1.4* | (1.0-1.9) | 1.7* | (1.0-2.9) | 1.1 | (0.6-1.9) | 1.4 | (0.8-2.6) | 0.7 | (0.3-1.9) |
| Other | ||||||||||
| Age (in decades) | 0.8* | (0.7-0.9) | 0.9 | (0.8-1.0) | 0.8* | (0.6-0.9) | 0.7* | (0.5-0.8) | 0.9 | (0.7-1.2) |
| Prior psychotropic useb | 0.6* | (0.5-0.9) | 0.7 | (0.4-1.2) | 0.8 | (0.4-1.6) | 0.6 | (0.3-1.1) | 0.2* | (0.1-0.5) |
| Disorder severityc | 1.3 | (0.9-1.7) | 1.0 | (0.7-1.6) | 1.6 | (0.9-2.8) | 1.2 | (0.6-2.1) | 3.6* | (1.2-10.9) |
| Rx by MH professional | 0.6* | (0.4-0.9) | 0.6 | (0.3-1.0) | 0.9 | (0.5-1.6) | 0.4* | (0.2-0.8) | 0.5 | (0.1-1.9) |
| (n)d | (98,685) | (98,685) | (98,685) | (98,685) | (98,685) | |||||
Abbreviations: RR, relative risk; 95% CI, 95% confidence interval of RR.
*
Significant at the .05 level, two-sided design-based test.
a
High, high-average, and low-average education were Coded 1; low education was Coded 0.
b
In past two years.
c
Severe/moderate (Coded 1) versus mild/none (Coded 0).
d
Number of person-weeks in the analysis, noting that all person-weeks of patients who did not report lack of continued need as a reason for discontinuation were coded to NO on dropout in the “Need” model, all person-weeks of patients who did not report treatment ineffectiveness as a reason for discontinuation were coded to NO on dropout from the “Ineffective” model, etc.