Table 1:
Baseline characteristics and CMR findings of patients and healthy controls. Continuous variables are presented as mean ± SD for normally distributed data or median (range) for non-normally distributed data, indicated by +. Dichotomous variables are presented as number (%). Appropriate comparison test was undertaken depending on normality of data distributions. BSA- body surface area; LVEF- left ventricular ejection fraction; LVEDV- left ventricular end-diastolic volume; LVEDV(i)- left ventricular end-diastolic volume (indexed); MWT- maximal wall thickness; τic (cell residence time of water); ECV- extracellular volume; 2SXM- two-site exchange model; LM- linear model; P value (paired t test or Mann-Whitney test) is considered significant at <0.05 level and indicated by *.
| Characteristic | Patients (n=25) | Healthy controls (n=5) | P value |
|---|---|---|---|
| Age (years) | 69 (58-77) | 62 (62-77) + | 0.54+ |
| Males (%) | 14 (56) + | 3 (60) + | 0.88+ |
| BSA (m2) | 1.99 (1.42-2.42) | 1.84 (1.37-1.89) + | 0.27+ |
| LVEF (%) | 59 ± 7 | 65 ± 3 | 0.10 |
| Indexed LVEDV(ml/m2) | 73 ± 19 | 61 ± 8 | 0.18 |
| MWT (mm) | 14 ± 2 | 10 ± 2 | 0.002* |
| Myocardial mass indexed (g/m2) | 81 ± 18 | 55 ± 11 | 0.004* |
| τic (s) | 0.21 (0.0-0.46) | 0.12 (0.0–0.26) | 0.10 |
| ECV (2SXM) (%) | 25 (21-39) + | 26 (22-29) | 0.60+ |
| ECV (LM) 0.05 mmol/kg @4 mins (%) | 25 (19-38) | 26 (23-29) | 0.92 |
| ECV (LM) 0.15 mmol/kg @10 mins (%) | 21 (17-32) | 23 (20-25) | 0.68 |
| ECV (LM) 0.15 mmol/kg @30 mins (%) | 22 (19-35) + | 22 (21-25) | 0.56+ |