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. 2023 Nov 23;13(2):166–176. doi: 10.1093/stcltm/szad079

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© The Author(s) 2023. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — VPA promoted the differentiation of hepatoblasts into cholangiocyte-like cells via activating Notch signaling. (A) Schematic diagram of the mechanism of VPA promoting the differentiation of hepatoblasts into cholangiocyte-like cells. (B) Immunostaining of Notch2 in differentiated cells with or without VPA treatment. (C) Real-time PCR results of the expression of genes in Notch2 signaling pathway. (n = 3, *P < .05, **P < .01 vs. day 7).