Table 1.
Baseline study population characteristics stratified by race/ethnicity in the Sister Study 2003–2009 (n=4126).
| Black (n=633) |
NHW (n=3493) |
|
|---|---|---|
| Age (years), median (IQR) | 54.8 (48.6, 59.6) | 56.9 (50.6, 63.6) |
| Education level, n (%) | ||
| High school/GED or less | 63 (10%) | 537 (15%) |
| Some college/associate or technical degree | 215 (34%) | 1135 (33%) |
| College degree or more | 355 (56%) | 1821 (52%) |
| Region, n (%) | ||
| Midwest | 141 (22%) | 1040 (30%) |
| Northeast | 61 (10%) | 639 (18%) |
| South | 374 (59%) | 1046 (30%) |
| West | 57 (9%) | 768 (22%) |
| BMI (kg/m 2 ), median (IQR) | 30.2 (26.4, 35.4) | 26.4 (23.3, 30.5) |
| Smoking status, n (%) | ||
| Never | 405 (64%) | 1844 (53%) |
| Past | 176 (28%) | 1393 (40%) |
| Current | 52 (8%) | 256 (7%) |
| Total pack years among current and past smokers, median (IQR) | 8.6 (2.9, 18.1) | 10.5 (3.1, 23.0) |
| Physical activity (hours per week), median (IQR) | 11.0 (6.9, 16.0) | 12.5 (7.7, 19.0) |
| ADI of primary residence (percentile), median (IQR) | 44.0 (24.0, 69.0) | 27.0 (12.0, 48.0) |
| Air pollutants, median (IQR) | ||
| PM2.5 2006, μg/m3 | 12.0 (10.9, 13.2) | 10.4 (8.5, 11.7) |
| PM10 2000, μg/m3 | 23.4 (20.7, 26.6 | 21.4 (18.4, 24.2 |
| NO2 2006, ppb | 10.8 (8.0, 14.7) | 8.0 (5.5, 11.2) |
| Epigenetic aging measures, median (IQR) | ||
| DunedinPACE | 1.10 (1.05, 1.17) | 1.05 (1.00, 1.11) |
| GrimAgeAccel | 0.16 (−1.86, 2.89) | −0.81 (−2.51, 1.48) |
| PhenoAgeAccel | −0.08 (−4.91, 4.45) | −0.39 (−4.17, 3.69) |
Abbreviations: ADI, area deprivation index; BMI, body mass index; IQR, interquartile range; NHW, non-Hispanic White; NO2, nitrogen dioxide; PM10, particulate matter<10 μm in diameter; PM2.5, particulate matter<2.5 μm in diameter; Ppb, parts per billion.