Table 2.

Definitions of subdomains in MEK1

CG subdomain	Sequence	CG subdomain	Sequence
1: N terminal helix (Nα)	43–60	10: αE	162–185
2: β1	68–74	11: Catalytic loop	186–194
3: P-loop	75–81	12: β7	196–198
4: β2	82–87	13: β8	204–206
5: β3	92–100	14: A-loop	208–233
6: αC	107–125	15: αF	242–259
7: β4	129–134	16: αG	309–319
8: β5	138–144	17: αH	331 −342
9: αD	149–159	18: αI	351–367