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The author’s recommended weekly romiplostim dose titration procedure for CIT.
| Platelet Count | Recommended Weekly Romiplostim Dose Titration |
|---|---|
| <50×109/L | Increase dose by 2 mcg/kg |
| 50–99×109/L | Increase dose by 1 mcg/kg |
| 100–200×109/L | Maintain current dose |
| 201–400×109/L | Decrease dose by 1 mcg/kg |
| >400×109/L | Decrease dose by 1–2 mcg/kg or consider holding romiplostim. If holding, resume romiplostim at 1–2 mcg/kg lower than prior dose once platelet count drops to <200–300×109/L |
