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. Author manuscript; available in PMC: 2024 Dec 30.
Published in final edited form as: Expert Opin Ther Targets. 2023 Dec 30;27(12):1177–1188. doi: 10.1080/14728222.2023.2288277

Figure 1.

Figure 1.

Motifs and Structure of LSD1. A linear representation of LSD1 motifs (above) and ribbon-style cartoon 3D structure of LSD1 (below). LSD1 consists of three major domains: a DNA-binding SWIRM domain (purple), a protein-protein interacting Tower domain (green), and a catalytically active enzymatic demethylase amine oxidase domain (gold). Structure was obtained from Protein Data Bank (PDB) Entry ID 6NQM as generated by PISA software under Creative Commons license. Created with BioRender.com.