Table 1.

Participant characteristics at first tau-PET scan.

Variable	Total (N=321), 35% Aβ+	rs6347 CC (N=32), 44% Aβ+	rs6347 TC (N=111), 36% Aβ+	rs6347 TT (N=178), 34% Aβ+	p-value (comparing rs6347 genotypes) 39% Aβ+	rs6265 Met carriers (N=113),	rs6265 Val/Val (N=208), 34% Aβ+	p-value (comparing rs6265 genotypes)
N female (%)	179 (56)	17 (53)	58 (52)	104 (58)	.35	48 (42)	94 (45)	.64
Age, years	73.8	72.4	73.9	73.9	.38	73.0	74.2	.14
(SD)	(7.0)	(7.1)	(7.1)	(7.1)		(7.2)	(6.8)
Education,	16.9	16.6	16.6	17.2	.06	17.2	16.7	.16
years (SD)	(2.3)	(2.4)	(2.4)	(2.2)		(2.3)	(2.2)
MMSE (SD)	29.1 (1.2)	29.1 (1.1)	29.0 (1.4)	29.1 (1.2)	.50	29.2 (1.2)	29.0 (1.2)	.23
GDS (SD)	0.7 (1.2)	0.8 (1.6)	0.7 (1.0)	0.8 (1.3)	0.71	0.7 (1.1)	0.8 (1.3)	0.34
FBP/FBB in	21.8	25.4	23.7	19.9	.23	24.5	20.3	.25
centiloids (SD)	(30.7)	(29.5)	(33.1)	(29.4)		(33.0)	(29.4)
Entorhinal FTP SUVR (SD)	1.1 (.1)	1.2 (.2)	1.1 (.1)	1.1 (.1)	.13	1.2 (.1)	1.1 (.1)	.07

Abbreviations: MMSE, Mini Mental State Exam; GDS, Geriatric Depression Scale; FBP/FBB, Florbetapir/Florbetaben Aβ-PET normalized to the centiloid scale; FTP SUVR, Flortaucipir standardized uptake value ratio (tau-PET measured in the entorhinal cortex).