Table 2.
BMI and biliary tract cancer mortality
| BMI | Cases | HR1 | 95% CI | trend-p | HR2 | 95% CI | trend-p | HR3 | 95% CI | trend-p | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Biliary tract cancer | |||||||||||||
| Males | 0.001 | 0.001 | 0.001 | ||||||||||
| <18.5 | 57 | 0.87 | (0.66 | -1.14) | 0.87 | (0.66 | -1.14) | 0.79 | (0.59 | -1.07) | |||
| 18.5– <23 | 513 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 270 | 1.06 | (0.92 | -1.23) | 1.06 | (0.91 | -1.23) | 1.05 | (0.90 | -1.22) | |||
| ≥25 | 275 | 1.19 | (1.02 | -1.38) | 1.19 | (1.02 | -1.38) | 1.17 | (1.00 | -1.37) | |||
| Females | <0.001 | <0.001 | <0.001 | ||||||||||
| <18.5 | 83 | 0.95 | (0.75 | -1.21) | 0.95 | (0.75 | -1.21) | 0.97 | (0.76 | -1.23) | |||
| 18.5– <23 | 484 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 275 | 1.16 | (1.00 | -1.35) | 1.16 | (1.00 | -1.35) | 1.18 | (1.01 | -1.38) | |||
| ≥25 | 396 | 1.30 | (1.14 | -1.50) | 1.30 | (1.14 | -1.49) | 1.32 | (1.14 | -1.52) | |||
| Interaction | 0.939 | 0.968 | 0.859 | ||||||||||
| Total biliary tract cancer | |||||||||||||
| Males | 0.001 | 0.001 | 0.001 | ||||||||||
| <18.5 | 47 | 0.85 | (0.63 | -1.15) | 0.85 | (0.63 | -1.15) | 0.77 | (0.55 | -1.06) | |||
| 18.5– <23 | 478 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 250 | 1.04 | (0.89 | -1.21) | 1.04 | (0.89 | -1.21) | 1.05 | (0.89 | -1.23) | |||
| ≥25 | 246 | 1.16 | (0.99 | -1.36) | 1.16 | (0.99 | -1.35) | 1.15 | (0.98 | -1.35) | |||
| Females | <0.001 | <0.001 | <0.001 | ||||||||||
| <18.5 | 78 | 1.01 | (0.79 | -1.29) | 1.01 | (0.79 | -1.30) | 1.02 | (0.79 | -1.31) | |||
| 18.5– <23 | 430 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 236 | 1.15 | (0.98 | -1.35) | 1.15 | (0.98 | -1.35) | 1.16 | (0.98 | -1.36) | |||
| ≥25 | 327 | 1.33 | (1.15 | -1.54) | 1.32 | (1.14 | -1.53) | 1.33 | (1.15 | -1.55) | |||
| Interaction | 0.805 | 0.843 | 0.688 | ||||||||||
| Intrahepatic bile duct | |||||||||||||
| Males | 0.228 | 0.249 | 0.125 | ||||||||||
| <18.5 | 5 | 0.64 | (0.26 | -1.59) | 0.64 | (0.26 | -1.60) | 0.71 | (0.29 | -1.78) | |||
| 18.5– <23 | 82 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 34 | 0.74 | (0.50 | -1.11) | 0.74 | (0.49 | -1.11) | 0.80 | (0.53 | -1.21) | |||
| ≥25 | 48 | 1.11 | (0.77 | -1.60) | 1.10 | (0.77 | -1.59) | 1.19 | (0.82 | -1.72) | |||
| Females | 0.041 | 0.027 | 0.028 | ||||||||||
| <18.5 | 5 | 0.87 | (0.34 | -2.22) | 0.87 | (0.34 | -2.21) | 0.87 | (0.34 | -2.21) | |||
| 18.5– <23 | 43 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 25 | 1.09 | (0.66 | -1.79) | 1.10 | (0.67 | -1.81) | 1.06 | (0.64 | -1.75) | |||
| ≥25 | 43 | 1.52 | (0.99 | -2.34) | 1.57 | (1.02 | -2.40) | 1.57 | (1.02 | -2.41) | |||
| Interaction | 0.664 | 0.686 | 0.724 | ||||||||||
| Gallbladder | |||||||||||||
| Males | 0.407 | 0.385 | 0.645 | ||||||||||
| <18.5 | 20 | 1.17 | (0.72 | -1.89) | 1.16 | (0.72 | -1.89) | 1.08 | (0.64 | -1.83) | |||
| 18.5– <23 | 128 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 61 | 0.99 | (0.73 | -1.34) | 0.99 | (0.72 | -1.34) | 1.03 | (0.75 | -1.41) | |||
| ≥25 | 48 | 0.88 | (0.63 | -1.24) | 0.88 | (0.62 | -1.23) | 0.90 | (0.63 | -1.27) | |||
| Females | 0.010 | 0.011 | 0.017 | ||||||||||
| <18.5 | 35 | 0.97 | (0.67 | -1.40) | 0.97 | (0.67 | -1.40) | 0.91 | (0.62 | -1.34) | |||
| 18.5– <23 | 190 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 96 | 1.08 | (0.84 | -1.38) | 1.08 | (0.84 | -1.38) | 1.03 | (0.80 | -1.34) | |||
| ≥25 | 140 | 1.30 | (1.04 | -1.62) | 1.29 | (1.03 | -1.61) | 1.26 | (1.00 | -1.59) | |||
| Interaction | 0.082 | 0.084 | 0.116 | ||||||||||
| Extrahepatic bile duct | |||||||||||||
| Males | <0.001 | <0.001 | <0.001 | ||||||||||
| <18.5 | 26 | 0.78 | (0.52 | -1.18) | 0.78 | (0.52 | -1.17) | 0.68 | (0.44 | -1.05) | |||
| 18.5– <23 | 281 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 166 | 1.18 | (0.97 | -1.43) | 1.17 | (0.97 | -1.42) | 1.14 | (0.94 | -1.39) | |||
| ≥25 | 166 | 1.33 | (1.09 | -1.62) | 1.33 | (1.09 | -1.62) | 1.28 | (1.04 | -1.56) | |||
| Females | 0.012 | 0.014 | 0.009 | ||||||||||
| <18.5 | 42 | 1.08 | (0.77 | -1.50) | 1.08 | (0.77 | -1.51) | 1.14 | (0.81 | -1.60) | |||
| 18.5– <23 | 215 | Reference | Reference | Reference | |||||||||
| 23≤ <25 | 127 | 1.26 | (1.01 | -1.58) | 1.26 | (1.01 | -1.58) | 1.31 | (1.05 | -1.65) | |||
| ≥25 | 161 | 1.32 | (1.07 | -1.63) | 1.32 | (1.07 | -1.63) | 1.36 | (1.10 | -1.69) | |||
| Interaction | 0.356 | 0.336 | 0.527 | ||||||||||
HR1, Adjusted for age; HR2, Adjusted for age, education, population density, marriage status, past history of CHD, stroke, DM, hypertension, smoking status and alchol drinking status.
Abbreviations: BMI, body mass index; CI, confidence interval; HR, hazard ratio