Figure 2. Cntnap1C324R/− and Cntnap1R765C/− mutants display severe motor disability and decline in nerve conduction properties.
(A and B) Beam walking motor coordination performance.
(C and D) Motor learning ability as measured by rotarod test.
(E–L) Representative electrical impulse traces from P20 sciatic nerves (E) showing amplitude, velocity, and latency (F–H, respectively) and ankle (I) showing amplitude, velocity, and latency (J–L, respectively). Data are represented as the mean ± SEM of five biological replicates.