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. 2005 May;73(5):2644–2654. doi: 10.1128/IAI.73.5.2644-2654.2005

FIG. 2.

FIG. 2.

Intranasal vaccination provides more protection against respiratory NMFTA1 challenge than s.c. vaccination. BALB/c mice (four to five per group) were vaccinated i.n. with 2 × 102 CFU or s.c. with 2 × 105 CFU of LVS. Twenty-one days after vaccination, i.n. and s.c. vaccinated mice and unvaccinated mice were challenged i.n. with 2 × 102 (A) or 2 × 103 (B) CFU of NMFTA1. All vaccinated mice that survived infection beyond 30 days survived at least two more months.