FIG. 6.

Effects of sopD, sopB, and double sopD-sopB mutations on the ability of S. dublin to induce fluid secretion and PMN influx. S. dublin 2229 (wild type), SB2 (sopB), SD1 (sopD), and SB2SD1 (sopB sopD) were used in ligated loop assays. The secretory response is defined as the volume of fluid within a loop per length of loop. The PMN influx is defined as radioactive counts of PMNs within test loops per radioactive count of PMNs in negative-control loops. Values are the means of three loops and are representative of results from three independent experiments. Error bars indicate standard deviations.