FIG. 8.
Effects of Legionella LPS on the growth of bacteria. BM macrophages (105 cells) were infected with L. pneumophila on day 0. Legionella LPS (in multiplicities of infection) and IL-12 plus IL-18 (10 ng/ml) were added to the wells at 2 h and 24 h after infection, respectively. Seven days after infection, bacterial numbers in the wells were determined. The results are expressed as means ± standard deviations for five wells. Similar results were obtained in at least two independent experiments. An asterisk indicates a P value of <0.05 in a comparison with the control group.