Table 2.
Distribution of resistance phenotypes and genotypes among GBS strains with particular serotypes with erythromycin and clindamycin-resistances, or either, in pregnant women and newborns.
Serotype | Antibiotic resistance genes | Resistance phenotype | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
ermB | ermA | mefA | tetM | lnuB | lsaE | cMLSB | iMLSB | M | L | |
Pregnant women (n = 82) | ||||||||||
Ia (n = 8) | 0 | 0 | 8 (100)* | 2 (25.0) | 0 | 0 | 0 | 0 | 8 (100) | 0 |
Ib (n = 3) | 3 (100) | 0 | 0 | 0 | 0 | 0 | 3 (100) | 0 | 0 | 0 |
II (n = 6) | 5 (83.3) | 1 (16.7) | 0 | 2 (33.3) | 0 | 0 | 5 (83.3) | 1 (16.7) | 0 | 0 |
III (n = 13) | 9 (69.2) | 3 (23.1) | 2 (15.4) | 3 (23.1) | 0 | 0 | 10 (76.9) | 2 (15.4) | 1 (7.7) | 0 |
IV (n = 2) | 0 | 2 (100) | 0 | 0 | 0 | 0 | 2 (100) | 0 | 0 | 0 |
V (n = 49) | 44 (89.8) | 3 (6.1) | 1 (2.0) | 35 (71.4) | 1 (2.0) | 1 (2.0) | 44 (89.8) | 3 (6.1) | 1 (2.0) | 1 (2.0) |
VI (n = 1) | 0 | 0 | 0 | 0 | 1 (100) | 1 (100) | 0 | 0 | 0 | 1 (100) |
Newborns (n = 7) | ||||||||||
Ia (n = 2) | 0 | 0 | 2 (100) | 0 | 0 | 0 | 0 | 0 | 2 (100) | 0 |
II (n = 1) | 1 (100) | 0 | 0 | 0 | 0 | 0 | 1 (100) | 0 | 0 | 0 |
III (n = 1) | 0 | 0 | 1 (100) | 1 (100) | 0 | 0 | 0 | 0 | 1 (100) | 0 |
V (n = 3) | 3 (100) | 0 | 0 | 2 (66.7) | 0 | 0 | 3 (100) | 0 | 0 | 0 |
Total (n = 89) | 65 (73.0) | 9 (10.1) | 14 (15.7) | 45 (50.6) | 2 (2.2) | 2 (2.2) | 68 (76.4) | 6 (6.7) | 13 (14.6) | 2 (2.2) |
*The percentage values.