TABLE 4.
LPS-specific salivary IgA and IgA-ASC in volunteers challenged with Vibrio cholerae 3008
| Group | Mean no. of ASC/106 PBMC (range) and response rate
|
Mean optical density in salivary IgA ELISA (range) and response rate
|
||||
|---|---|---|---|---|---|---|
| Day 0a | Day 7 | No. responding/no. tested | Day 0a | Day 9 | No. responding/no. tested | |
| Vaccine | 0 (0-0) | 15 (4-35) | 12/12 | 0.21 (0.11-0.39) | 0.27 (0.15-0.48) | 7/12 |
| Placebo | 0 (0-0) | 1,063 (35-2,600) | 9/9 | 0.23 (0.107-0.754) | 0.49 (0.24-0.689) | 7/9 |
a
Challenge day, 1 month after vaccine or placebo intake.