Table 3.
Cohort outcomes.
| Primary RIF (RIF-1) | RIF-1 IVIg | RIF-2 control | P-value |
|---|---|---|---|
| Variable | IVIg Group n = 24 | Control group n = 40 | |
| Live birth (%) | 14/24 (58.3) | 8/40(20) | 0.0027* |
| Live birth subgroup with < 5 failed blastocyst transfers (%)* | 4/7 (57.14) | 8/32 (25) | 0.17 |
| Live birth subgroup with ≥ 5 failed blastocyst transfers (%)* | 10/17 (58.8) | 0/8 | 0.007* |
| Secondary RIF (RIF-2) | RIF-2 IVIg | RIF-2 control | P-value |
|---|---|---|---|
| Variable | IVIg group n = 25 | Control group n = 54 | |
| Live birth (%) | 18/25 (72.0) | 24/54 (44.4) | 0.03** |
| Live birth subgroup with < 5 failed blastocyst transfers (%)* | 8/13 (61.5) | 19/37 (48.6) | 0.74 |
| Live birth subgroup with ≥ 5 failed blastocyst transfers (%)* | 10/12 (83.3) | 5/17 (29.4) | 0.008** |
| Primary and secondary RIF combined | |||
|---|---|---|---|
| Variable | IVIg group n = 49 | Control group n = 95 | P-value |
| Live birth (%) | 32/49 (65.3) | 32/95 (34) | < 0.001** |
| Live birth subgroup with < 5 failed blastocyst transfers (%)* | 12/20 (60) | 27/69 (39.1) | 0.126 |
| Live birth subgroup with ≥ 5 failed blastocyst transfers (%)* | 20/29 (69) | 5/25 (20) | 0.0004** |
All p-values were calculated with Fisher exact test.
*Only high-quality blastocyst ( 3BB).
**Statistically significant.