Table 7:

The correlation between dry eye symptoms and signs, and among signs for male and female at baseline (n = 1022 eyes)

	rho* (95% Confidence Interval)
	Female (n= 835 eyes)	Male (n= 187 eyes)	Difference (Female - Male)
Between OSDI and Four Dry Dye Signs
OSDI vs. Tear break-up time	−0.04 (−0.12, 0.04)	−0.14 (−0.31, 0.03)	0.10 (−0.10, 0.28)
OSDI vs. Schirmer test	−0.06 (−0.15, 0.02)	−0.06 (−0.24, 0.13)	−0.00 (−0.21, 0.20)
OSDI vs. Corneal staining score	0.06 (−0.02, 0.15)	0.02 (−0.21, 0.22)	0.04 (−0.17, 0.28)
OSDI vs. Conjunctival staining score	−0.01 (−0.10, 0.07)	0.03 (−0.15, 0.19)	−0.04 (−0.23, 0.15)
Among Four Dry Eye Signs
Tear break-up time vs. Schirmer test	0.17 (0.09, 0.25)	0.27 (0.10, 0.43)	−0.09 (−0.28, 0.07)
Tear break-up time vs. Corneal staining score	−0.27 (−0.35, −0.20)	−0.26 (−0.42, −0.09)	−0.02 (−0.20, 0.17)
Tear break-up time vs. Conjunctival staining score	−0.14 (−0.22, −0.06)	−0.08 (−0.24, 0.10)	−0.06 (−0.26, 0.12)
Schirmer test vs. Corneal staining score	−0.30 (−0.38, −0.22)	−0.40 (−0.56, −0.22)	0.10 (−0.09, 0.27)
Schirmer test vs. Conjunctival staining score	−0.25 (−0.33, −0.17)	−0.17 (−0.36, 0.03)	−0.08 (−0.29, 0.13)
Corneal staining score vs. Conjunctival staining score	0.33 (0.25, 0.41)	0.29 (0.11, 0.45)	0.04 (−0.12, 0.22)

^*Confidence intervals and p-values were calculated using cluster bootstrap to account for correlation from two eyes of the same patient.