FIG. 1.

cDNA and predicted amino acid sequences for canine β-defensins. (A) Canine β-defensin cDNA sequences showing their identical 249 bp 5′-terminal regions (shaded black) and diversity at their 3′-terminal ends. ORFs are indicated with start (ATG) and stop (TGA) codons highlighted in red in each sequence. (B) Alignment of predicted pre-proprotein sequences of three canine β-defensins. Identical amino acids are indicated as periods in cBD-2 and cBD-3. The cleavage site for a signal peptidase is indicated by the arrow. Conserved cysteine residues are boxed.