Table 3.
Summary of pH sensor absolute discrepancies, limits of agreement, and correlations of [H+] discrepancy to pH, osmolality, and batch age.
| pH Sensor type | Average absolute discrepancy (pH units)a | 95% Limits of Agreement |
Correlationb of discrepancy to: |
|||
|---|---|---|---|---|---|---|
| From | To | CCA pH | Bioreactor Osmolality | Batch Age | ||
| STR EP | 0.047 | −0.129 | 0.049 | Yes (***) | No | Yes (**) |
| SU EP | 0.044 | −0.172 | 0.089 | Yes (****) | No | Yes (**) |
| SU OPT | 0.072 | −0.201 | 0.192 | Yes (****) | Yes (*) | No |
a
Calculated using the average discrepancy in [H+] measurements and transformed into pH difference from pH 7.1.
b
Correlation refers to the statistical significance by Kruskal-Wallis test; p value summaries are p < 0.05 (*), p < 0.01(**), p < 0.001 (***) and p < 0.0001(****).