Table 1.

Case Definitions for the Durango Outbreak

Term	Definition
Exposed	All persons exposed to epidural anesthesia from May 2022 to February 2023 at any of the 4 private hospitals under investigation in Durango, Mexico
Suspected	All subjects exposed with symptoms suggestive of CNS infection (headache, neck pain, seizures, mental alterations)
Probable	Subjects exposed or suspected with 1 or more CSF alteration (eg, hypoglycorrhachia, hyperproteinorrachia, or pleocytosis)
Meningitis case	All classified subjects according to any of the previous definitions and with the following criteria: (1) Association with clinical-epidemiological data:  (a) Patients without a Fusarium solani confirmatory test (culture or molecular), whose symptoms of meningitis or CSF alterations were not explained by another cause (2) Confirmation by laboratory test:  (b) Fusarium solani culture from CSF or brain biopsy  (c) Subjects with positive qPCR test for F solani

Abbreviations: CNS, central nervous system; CSF, cerebrospinal fluid; qPCR, real-time polymerase chain reaction.