FIG. 3.
Association of anti-VSACSA IgG with estimated gestational age at enrolment (early pregnancy). Data are shown for both the placebo and vitamin A-supplemented groups. (A) MFI for EJ-24 against gestation in early pregnancy. Correlation coefficient (r) = 0.16 and P = 0.13. (B) MFI for FCR3CSA against gestation in early pregnancy. r = 0.23 and P = 0.03. (C) MFI for BusuaCSA against gestation in early pregnancy. r = 0.11 and P = 0.28. The solid horizontal line indicates the MFI plus 2 standard deviations for negative control plasma from malaria-exposed, Ghanaian men (cutoff for positive anti-VSA-CSA). The values are MFI minus the background fluorescence (mean for pRBC incubated in the absence of plasma). Gestational age was assessed by palpation or back-calculation from term deliveries if data were available. Estimates were assumed to be accurate to within ±2 weeks.