Fig. 4.

Effects of dopaminergic drugs on predator odor-induced grooming and locomotor activity in Dbh −/− mice. Dbh −/− mice were pretreated with vehicle (n = 7–13), the non-selective DA receptor antagonist flupenthixol (0.25 mg/kg; n = 7), the D2 antagonist L-741,626 (10 mg/kg; n = 8), or the D1 antagonist SCH-23390 (0.03, 0.01, or 0.006 mg/kg; n = 8), or and exposed to bobcat urine 30 min later for 10 min. Shown is the mean +/− SEM time engaged in grooming (A-C) and distance travelled (D). ****p < 0.0001, ***p < 0.001, **p < 0.01, ns = not significant.