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The effect of recombinant SP-D on P. aeruginosa invasion of cultured rabbit corneal epithelial cells. (A) Human recombinant SP-D inhibited corneal epithelial invasion by P. aeruginosa strain PAK when compared to control tissue culture media (HBSS). (B) Mouse recombinant SP-D significantly inhibited invasion by PAK at 5, 10, and 20 μg/ml (P < 0.05; ANOVA). SP-D at a concentration of 1 μg/ml did not significantly inhibit invasion.
