Table 4.

GV-971 significantly alters microbiome bacterial species in female mice treated with 100 mg/kg compared with vehicle

Comparisons
Female Ctrl vs Female 100 mg/kg GV-971	Increased in GV-971	Decreased in GV-971
	p__Bacteroidetes;c__Bacteroidia; o__Bacteroidales;f__Tannerellaceae; g__Parabacteroides;s__Parabacteroides sp YL27	p__Firmicutes;c__Clostridia; o__Clostridiales;f__Clostridiaceae; g__Clostridium;s__Clostridium sp Clone16
	p__Firmicutes;c__Clostridia; o__Clostridiales;f__Ruminococcaceae; g__Ruminiclostridium;s__Clostridium leptum	p__Actinobacteria;c__Coriobacteriia; o__Eggerthellales;f__Eggerthellaceae; g__Enterorhabdus;s__Enterorhabdus mucosicola
		p__Firmicutes;c__Clostridia; o__Clostridiales;f__Lachnospiraceae; g__Blautia;s__Blautia coccoides
		p__Firmicutes;c__Clostridia; o__Clostridiales;f__Clostridiaceae; g__Clostridium;s__Clostridium sp Clone49
		p__Firmicutes;c__Clostridia; o__Clostridiales;f__Clostridiaceae; g__Clostridium;s__Clostridium sp ASF502
		p__Firmicutes;c__Clostridia; o__Clostridiales;f__Clostridiaceae; g__Clostridium;s__Clostridium sp MarseilleP2776