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. 2024 Feb 16;17:2632010X241230262. doi: 10.1177/2632010X241230262

Figure 3.

Figure 3.

(A) G-banded karyotype of PB specimen: 46,XX,t(8;14)(q32;q24.1) (black arrows). (B) FISH with MYC (red), IGH (green) and CEP 8 (aqua) probes showing a fusion signal on der(8)t(8;14) (black arrow), and a residual MYC (red) on der(14)t(8;14) (open arrow). (C) Box and whisker plot showing expression of MYC using fragments per kilobase millions (FPKM) compared to other clinical cases of the same tissue type according to the corresponding Oncotree root (JCO Clin Cancer Inform 2021;5:221-230). (D) MYC protein expression in leukemia cells in BM core biopsy by IHC stain.