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. 2024 Feb 13;19:1451–1467. doi: 10.2147/IJN.S444009

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© 2024 Li et al.

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BEC-EVs and BMC-EVs administrations attenuated MMPs expression and activity in OGD-insulted BECs. (A) Western blotting of MMP-2/9 after EVs treatment. (B) Relative quantitative analysis of MMP-2/9 (n=3). (C) Relative quantification of MMP-2/9 mRNA expressed levels by RT-PCR (n=3). (D) Schematic diagram of MMPs activity. (E) MMP-2/9 activity evaluation by gelatin zymography in OGD-insulted BECs culture medium after EVs treatment. Std: positive control of MMP standard sample. (F) Relative quantification of MMP-2/9 activity (n=3). ***P < 0.001, **P < 0.01, *P < 0.05.